The Karo people thought to be one of the most endangered groups the Omo, with a population of about 1500 people. They inhabit the eastern bank of the Omo. They were formerly pastoralists, but many of their cattle have been wiped out by disease, and many have turned to agriculture.

In appearance, language and tradition, they slightly resemble the Hamer, to whom they are related. The Karo are considered masters of body painting, in which they engage when preparing for a dance, feast or celebration. Most famously, chalk is used to imitate the spotted plumage of the guinea fowl.